Pharmaceutical excipients, a broad array of substances blended with active ingredients into desired finished dosage forms, have, in recent...
Archive for category: Formulation Discussion
FDA Definition– Any adverse event associated with the use of drugs in humans whether or not considered drug related...
Introduction Solid form screening has become an important activity in drug development. The initial screening activity is designed to...
Polymer Strip Films for Delivery of Poorly Water-Soluble Drugs
Pharma Live, , Formulation Discussion, 0Abstract While polymer strip films have garnered significant attention for their patient compliance and cost-effective scale-up, recent studies have...
Drug-Excipient Compatibility for the Formulation Development of Solid Lipid Nanoparticles
Pharma Live, , Formulation Discussion, 0Solid Lipid Nanoparticles Solid lipid nanoparticles (SLN) are a type of a carrier system that employs solid lipids as...
Status Quo, Challenges, and Opportunities of Transdermal Drug Delivery
Pharma Live, , Formulation Discussion, 0Introduction Early work on transdermal drug delivery (TDD) goes back to the 1960s, and in 1971 the seminal US Patent titled...
Major Advances in Oral Drug Delivery over the Past 15 Years
Pharma Live, , Formulation Discussion, 0Introduction The oral route of administration is central for the delivery of a large number of important drugs in...
Introduction Lipinski’s seminal paper on experimental and computational (in silico) methods to estimate the solubility and permeability of drug...
Abstract Lipid formulations, while gaining increasing importance in parenteral and oral drug delivery, are also important in transdermal and...
Investigation of Excipient Compatibility and Associated Degradations for the Formulation Development of a Small Molecule Pharmaceutical Compound
Pharma Live, , Formulation Discussion, 0Introduction Drug formulation starts with the selection of various suitable excipients for the desired or required dosage forms. Drug-excipient interactions can...