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Current estimates indicate that more than 70% of new chemical entities require solubilization technology to achieve efficacious plasma exposure. Amorphous solid dispersion technology is a leading approach to improve solubility and dissolution rate of these insoluble compounds by providing a supersaturated concentration of drug in the gastrointestinal environment, which often translates to rapid absorption and improved bioavailability. Amorphous solid dispersions are typically prepared by using hot-melt extrusion or spray drying processes. This webinar will focus on the fundamentals of formulating and processing of spray-dried dispersions, including stability assessment, in-vitro performance, and downstream manufacturability.In this webinar, experts will discuss:Key parameters that indicate amorphous dispersions and specifically spray dry dispersions as an optimal enabling approach.How the spray drying process can be scaled from tens of milligrams to metric tons.Best practices for formulation screening and evaluation of stability, performance, and manufacturability of spray-dried dispersions.Methodologies and tools for spray drying process development and scale-up through clinical supply and commercial manufacturing.Key Learning ObjectivesDevelop an appreciation of key factors leading to the use of spray-dried dispersion technologyUnderstand the advantages and range of spray-dried dispersions and spray drying technologyLearn the fundamentals of spray-dried dispersion formulation selection, process development, and scale-upWho Should AttendLarge pharma, mid-size pharma, biotech companiesProduct development group leaders and formulators, technical and engineering positions involved in scale-up and manufacturing of oral solid dosage formsVisit PharmTech for registration

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